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ASCO Educational Book; 2009
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Physical Challenges of Adult Cancer Survivors

Maryam Lustberg, MD, and Charles L. Shapiro, MD

From the Comprehensive Breast Health Services, James Cancer Hospital, and The Ohio State University Comprehensive Cancer Center, Columbus, OH

Authors’ disclosures of potential conflicts of interest are found at the end of this article.

Address reprint requests to Charles L. Shapiro, MD, Professor, College of Medicine, The Ohio State University Comprehensive Cancer Center, 320 W 10th Ave, B405 Starling-Loving Hall, Columbus, OH 43210; e-mail: charles.shapiro{at}osumc.edu

Overview: Treatment-related problems of adult survivors include fatigue, chemotherapy-induced ovarian failure, infertility, vasomotor symptoms, sexual dysfunction, bone loss, neuropathy, cardiac disease, and the development of secondary cancers. Specific interventions, such as bisphosphonates for bone loss, are established based on screening and treatment recommendations for osteoporosis. For others (e.g., neuropathy and sexual dysfunction), interventions are being tested, but thus far none are effective. Research to develop interventions to prevent or mitigate the problems of survivors is a high priority.